Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171858 | 0.89 | L3MBTL1 (1.00) | L3MBTL1ALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL30034264 | 0.88 | SMN1; SMN2 (0.88) | L3MBTL1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL6170899 | 0.85 | L3MBTL1 (0.80) | L3MBTL1ALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL3502569 | 0.85 | ALDH1A1 (0.80) | L3MBTL1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL27432885 | 0.84 | GAA (0.76) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL9370863 | 0.84 | ALDH1A1 (0.88) | L3MBTL1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL3923158 | 0.83 | SMN1; SMN2 (0.78) | L3MBTL1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL13185621 | 0.83 | SMN1; SMN2 (1.00) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL2453779 | 0.83 | SMN1; SMN2 (0.78) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL29769748 | 0.81 | SMN1; SMN2 (0.76) | L3MBTL1ALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097138-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-QUINOLONES | LAFON LABOR (FR) | 2005-12-07 | — | — | EP | disclosed |
| US-6593342-B1 | Activity on the proliferation of clonogenic cells in tumours and comprising an efficient amount of a compound selected among the compounds | LABORATOIRE L. LAFON (FR) | 2003-07-15 | — | — | US | disclosed |