Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.80 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704595 | 0.90 | USP2 (0.81) | L3MBTL1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6171858 | 0.89 | L3MBTL1 (1.00) | L3MBTL1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9367753 | 0.85 | LTA4H (0.71) | RAB9ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL6171606 | 0.85 | L3MBTL1 (0.80) | L3MBTL1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5108829 | 0.81 | RAB9A (0.71) | L3MBTL1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27766762 | 0.81 | ALOX5 (0.57) | L3MBTL1RAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9370863 | 0.80 | ALDH1A1 (0.88) | L3MBTL1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6171613 | 0.80 | RAB9A (1.00) | L3MBTL1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9370835 | 0.80 | LTA4H (0.63) | L3MBTL1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9366570 | 0.79 | RAB9A (0.64) | RAB9ASMN1; SMN2ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097138-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-QUINOLONES | LAFON LABOR (FR) | 2005-12-07 | — | — | EP | disclosed |
| US-6593342-B1 | Activity on the proliferation of clonogenic cells in tumours and comprising an efficient amount of a compound selected among the compounds | LABORATOIRE L. LAFON (FR) | 2003-07-15 | — | — | US | disclosed |