SCHEMBL617178

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL616175	0.89	PTGS2 (0.48)	NEK2PTGS2FYNPDGFRBGAA
	SCHEMBL10188853	0.87	PTGS2 (0.46)	NEK2PTGS2PDGFRBPDGFRARAB9A
	SCHEMBL619190	0.85	TUBB4A (0.44)	NEK2PTGS2L3MBTL1GAATUBB4A
	SCHEMBL617838	0.84	FYN (0.55)	PTGS2FYNPDGFRBGAATUBB4A
	SCHEMBL616273	0.83	PTGS2 (0.72)	PTGS2FYNTUBB4ATUBBTUBA3C
	SCHEMBL616937	0.82	PTGS2 (0.70)	PTGS2FYNTUBB4ATUBBTUBA3C
	SCHEMBL617700	0.82	FYN (0.54)	PTGS2FYNGAATUBB4ATUBB
	SCHEMBL616176	0.82	PTGS2 (0.54)	PTGS2MAPTRAB9ATUBB4ATUBB
	SCHEMBL617567	0.82	PTGS2 (0.54)	PTGS2MAP3K11TUBB4ATUBBTUBA3C
	SCHEMBL10242289	0.81	PTGS2 (0.50)	PTGS2FYNTUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.