Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172336 | 0.92 | CACNA1B (0.34) | CACNA1BIGF1RPTGS2CTSSLMNA | |
| SCHEMBL6175297 | 0.91 | LMNA (0.39) | CACNA1BIGF1RPTGS2LMNATRPV3 | |
| SCHEMBL6172120 | 0.90 | KDM4E (0.35) | IGF1RPTGS2LMNAPTGS1 | |
| SCHEMBL6175007 | 0.90 | SLC22A12 (0.42) | CACNA1BIGF1RPTGS2LMNAPTGS1 | |
| SCHEMBL6171408 | 0.87 | IGF1R (0.35) | IGF1RPTGS2LMNA | |
| SCHEMBL6169741 | 0.87 | IGF1R (0.36) | IGF1RPTGS2LMNAPTGS1 | |
| SCHEMBL6175175 | 0.85 | IGF1R (0.36) | IGF1RPTGS2CTSSLMNA | |
| SCHEMBL6172100 | 0.85 | LMNA (0.38) | CACNA1BPTGS2LMNA | |
| SCHEMBL6175512 | 0.85 | IGF1R (0.37) | CACNA1BIGF1RLMNASLC22A12 | |
| SCHEMBL6173330 | 0.83 | IGF1R (0.40) | IGF1RCTSSLMNATRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |