Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 14/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6173312 | 0.83 | IGF1R (0.34) | IGF1R | |
| SCHEMBL6171670 | 0.82 | IGF1R (0.38) | IGF1R | |
| SCHEMBL6173915 | 0.75 | IGF1R (0.41) | IGF1R | |
| SCHEMBL6175147 | 0.74 | HTR2A (0.34) | — | |
| SCHEMBL2942754 | 0.71 | IGF1R (0.57) | IGF1R | |
| SCHEMBL6173685 | 0.70 | HTR6 (0.33) | IGF1R | |
| SCHEMBL2940341 | 0.70 | IGF1R (0.40) | IGF1R | |
| SCHEMBL2939198 | 0.69 | IGF1R (0.43) | IGF1R | |
| SCHEMBL6175215 | 0.68 | CTSS (0.34) | IGF1R | |
| SCHEMBL6172419 | 0.68 | HRH4 (0.38) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |