SCHEMBL61732

SCHEMBL61732

[c]1cccc(Oc2ccccc2)c1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 0.57
TSHR P16473 1/20 0.57
NR1H2 P55055 1/20 0.44
BAX Q07812 1/20 0.44
MAOA P21397 1/20 0.44
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
MAOB P27338 1/20 0.40
GSTP1 P09211 1/20 0.38
SOS1 Q07889 1/20 0.38
CA9 Q16790 1/20 0.38
PARP10 Q53GL7 1/20 0.38
PLA2G2A P14555 1/20 0.38
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
NLRP3 Q96P20 1/20 0.36
SRD5A2 P31213 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28072263 0.98 LTA4H (0.55) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL27493063 0.94 LTA4H (0.50) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL8155454 0.93 LTA4H (0.43) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL27958951 0.92 LTA4H (0.48) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL9261806 0.92 MAOB (0.48) LTA4HTSHRNR1H2BAXMAOA
Magnesium Chloride Anhydrous SCHEMBL27958970 0.92 LTA4H (0.48) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL28263208 0.90 LTA4H (0.46) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL9450784 0.88 LTA4H (0.42) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL7007175 0.84 MAOB (0.45) MAOAMAOBGSTP1RAB9A
SCHEMBL920289 0.83 TEAD4 (0.47) LTA4HTSHRNR1H2BAXMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4060 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11987588-B2 Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2024-05-21 US claimed
US-11958871-B2 Inhibitors of bacterial glutaminyl cyclases for use in the treatment of periodontal and related diseases Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-04-16 US claimed
CN-111757883-B Novel inhibitors of bacterial glutaminyl cyclase for the treatment of periodontal disease and related diseases 弗劳恩霍夫应用研究促进协会 2024-02-13 CN claimed
EP-4295852-A2 PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) Syros Pharmaceuticals, Inc. (US) 2023-12-27 EP claimed
US-20230354808-A1 METHOD OF CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QOI FUNGICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-11-09 US claimed
US-20230339904-A1 ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS BIOTHERYX, INC. 2023-10-26 US claimed
CN-116891466-A Pyrazole-containing dithiazole carboxamide derivative and preparation method and application thereof 南开大学 2023-10-17 CN claimed
WO-2023134733-A1 TREATMENT OF SIGNS, SYMPTOMS AND/OR COMPLICATIONS OF VIRAL, BACTERIAL, PROTOZOAL, AND/OR FUNGAL INFECTIONS BY HIGH PENETRATION PRODRUGS TECHFIELDS PHARMA CO., LTD. (CN) 2023-07-20 WO claimed
EP-3484871-B1 PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) SYROS PHARMACEUTICALS INC (US) 2023-06-07 EP claimed
EP-3720858-B1 MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO ARENA PHARM INC (US) 2023-06-07 EP claimed
US-4283414-A Pesticidal fluorinated esters of the pyrethrin or pyrethroid type ICI AUSTRALIA LIMITED (AU) 1981-08-11 US claimed
EP-0031104-A1 Thiazolidine compounds, processes for their preparation and pharmaceutical compositions containing them SANTEN PHARMACEUTICAL CO., LTD. (JP) 1981-07-01 EP claimed
EP-0006354-A1 Fluoro-substituted pyrethroid-type esters, processes for their preparation, intermediates for use in such processes, compositions for insecticidal use, and methods of combating insect pests ICI AUSTRALIA LIMITED (AU) 1980-01-09 EP claimed
EP-0001809-A1 Synergetic insecticidal and acaricidal mixtures BASF Aktiengesellschaft (DE) 1979-05-16 EP claimed
US-4107439-A Process for preparing arylalkanoic acid derivatives THE UPJOHN COMPANY (US) 1978-08-15 US claimed
US-4100298-A Dispirocyclopropane carboxylate pesticides SHELL OIL COMPANY (US) 1978-07-11 US claimed
US-4096338-A ANTIPHLOGISTIC NISSHIN FLOUR MILLING CO., LTD. (JA) 1978-06-20 US claimed
US-4042617-A FROM A GLYCIDIC ACID ESTER NISSHIN FLOUR MILLING CO., LTD. (JA) 1977-08-16 US claimed
US-4016196-A HEATING GLYCIDIC ESTERS NISSHIN FLOUR MILLING CO., LTD. (JA) 1977-04-05 US claimed
US-4007217-A FROM A GLYCIDATE NISSHIN FLOUR MILLING CO., LTD. (JA) 1977-02-08 US claimed