SCHEMBL9450784

SCHEMBL9450784

[c]1ccc(Oc2c[c]ccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.42
TSHR P16473 1/20 0.42
NR1H2 P55055 1/20 0.33
BAX Q07812 1/20 0.33
MAOA P21397 1/20 0.33
MEN1 O00255 1/20 0.31
MITF O75030 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
GFER P55789 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NLRP1 Q9C000 1/20 0.31
NOD2 Q9HC29 1/20 0.31
MAOB P27338 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8155454 0.91 LTA4H (0.43) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL61732 0.88 LTA4H (0.57) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL28072263 0.86 LTA4H (0.55) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL27493063 0.83 LTA4H (0.50) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL157734 0.81 SOS1 (0.40) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL511009 0.81 MAOA (0.47) LTA4HTSHRMAOAMEN1ALDH1A1
SCHEMBL6154322 0.81 LTA4H (0.59) LTA4HTSHRNR1H2BAXMEN1
SCHEMBL920289 0.81 TEAD4 (0.47) LTA4HTSHRNR1H2BAXMEN1
SCHEMBL4909322 0.81 MAPT (0.47) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL921837 0.81 LTA4H (0.37) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020218003-A1 N,N'-DIARYLUREA DERIVATIVE AND THERMOSENSITIVE RECORDING MATERIAL USING SAME 三光株式会社 2020-10-29 WO disclosed
US-5189141-A Polyaramide with pendant carboxyl groups E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-02-23 US disclosed
US-5039785-A Preparation of aromatic polyamide having pendant carboxyl groups E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-08-13 US disclosed