Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.48 |
| ▸ | CLK1 | P49759 | 2/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.48 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.45 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CLK3 | P49761 | 1/20 | 0.43 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.43 |
| ▸ | MYLK2 | Q9H1R3 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6173436 | 1.00 | CSNK2A2 (0.48) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL6174177 | 0.84 | PIK3CG (0.55) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL6174830 | 0.83 | NAT1 (0.55) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL6174832 | 0.83 | NAT1 (0.55) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL6176750 | 0.83 | CSNK2A2 (0.58) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL6175239 | 0.83 | CSNK2A2 (0.58) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL6185694 | 0.82 | CSNK2A2 (0.48) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL6173322 | 0.82 | CSNK2A2 (0.48) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL6842482 | 0.82 | CSNK2A2 (0.48) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL6173325 | 0.82 | CSNK2A2 (0.48) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581529-A1 | BENZOXAZINES AND DERIVATIVES THEREOF AS INHIBITORS OF PI3KS | WARNER-LAMBERT COMPANY (US) | 2005-10-05 | — | — | EP | disclosed |
| US-20040138199-A1 | Benzoxazines and derivatives thereof as therapeutic agents | GOGLIOTTI ROCCO DEAN (US) | 2004-07-15 | — | — | US | disclosed |
| WO-2004056820-A1 | BENZOXAZINES AND DERIVATIVES THEREOF AS INHIBITORS OF PI3KS | WARNER-LAMBERT COMPANY LLC (US) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138199-A1 | Benzoxazines and derivatives thereof as therapeutic agents | XDH, TBXA2R, TBXAS1 | CSNK2A2 1130/4885CLK1 602/4885CSNK2B 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.