Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | MC1R | Q01726 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 2/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177161 | 0.88 | LMNA (0.45) | LMNAACP1CXCR3MC4RMC1R | |
| SCHEMBL6173087 | 0.85 | IGF1R (0.41) | LMNAIGF1R | |
| SCHEMBL6175470 | 0.79 | ACP1 (0.41) | ACP1CXCR3MC4RMC1RPOLB | |
| SCHEMBL6175890 | 0.77 | LMNA (0.39) | LMNAACP1CXCR3POLBL3MBTL1 | |
| SCHEMBL6172286 | 0.76 | LMNA (0.41) | LMNACXCR3POLBL3MBTL1CASR | |
| SCHEMBL6175754 | 0.74 | LMNA (0.39) | LMNAIGF1RPDE2A | |
| SCHEMBL6175824 | 0.74 | LMNA (0.39) | LMNAPOLBIGF1RPDE2AADAM17 | |
| SCHEMBL6171605 | 0.73 | LMNA (0.39) | LMNAIGF1RPDE2A | |
| SCHEMBL6172638 | 0.73 | LMNA (0.39) | LMNAIGF1RPDE2A | |
| SCHEMBL6174264 | 0.73 | IGF1R (0.43) | LMNAMC4RIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |