Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 12/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178331 | 0.89 | CYP3A4 (0.41) | IGF1RSLC22A12LMNAALDH1A1 | |
| SCHEMBL6174921 | 0.85 | IGF1R (0.43) | IGF1RARALDH1A1 | |
| SCHEMBL6173549 | 0.85 | IGF1R (0.43) | IGF1RARALDH1A1 | |
| SCHEMBL6174310 | 0.85 | IGF1R (0.43) | IGF1RARALDH1A1 | |
| SCHEMBL6174812 | 0.85 | ALDH1A1 (0.38) | PDE2ALMNAALDH1A1 | |
| SCHEMBL6172761 | 0.85 | IGF1R (0.42) | IGF1RLMNATSHRKMT2AALDH1A1 | |
| SCHEMBL6174841 | 0.85 | IGF1R (0.42) | IGF1RLMNA | |
| SCHEMBL6173913 | 0.84 | IGF1R (0.43) | IGF1RARALDH1A1 | |
| SCHEMBL6174315 | 0.84 | IGF1R (0.41) | IGF1RLMNAARALDH1A1 | |
| SCHEMBL6173174 | 0.84 | IGF1R (0.44) | IGF1RARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |