Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 16/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175683 | 0.87 | IGF1R (0.51) | IGF1RAR | |
| SCHEMBL6176736 | 0.85 | MAT2A (0.38) | TSHRKMT2ALMNAHTTAR | |
| SCHEMBL6172820 | 0.85 | IGF1R (0.42) | IGF1RAR | |
| SCHEMBL6174494 | 0.85 | IGF1R (0.42) | IGF1RAR | |
| SCHEMBL6174586 | 0.85 | TP53 (0.39) | IGF1RTSHRKMT2ALMNAHTT | |
| SCHEMBL6174595 | 0.84 | IGF1R (0.52) | IGF1RAR | |
| SCHEMBL6173683 | 0.84 | IGF1R (0.52) | IGF1RAR | |
| SCHEMBL6173933 | 0.83 | IGF1R (0.40) | IGF1RAR | |
| SCHEMBL6176345 | 0.82 | IGF1R (0.53) | IGF1RAR | |
| SCHEMBL17558389 | 0.82 | IGF1R (0.53) | IGF1RAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |