Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21268432 | 0.81 | LOXL2 (0.42) | ALDH1A1KMT2APLK1SRCLMNA | |
| SCHEMBL8463456 | 0.72 | ALDH1A1 (0.41) | ALDH1A1KMT2ALMNAHPGDRAB9A | |
| SCHEMBL3062621 | 0.72 | MAPT (0.41) | ALDH1A1KMT2ALMNAHPGDRAB9A | |
| SCHEMBL3601381 | 0.70 | — | — | |
| SCHEMBL3956678 | 0.68 | HPGD (0.43) | ALDH1A1PLK1HPGDRAB9ANPC1 | |
| Acetic Acid SCHEMBL30839310 | 0.68 | ALDH1A1 (0.68) | ALDH1A1PLK1SRCLPLLIPG | |
| SCHEMBL191797 | 0.67 | — | — | |
| SCHEMBL192917 | 0.67 | TP53 (0.36) | ALDH1A1PLK1LMNATRPA1LPL | |
| SCHEMBL334751 | 0.67 | KMT2A (0.70) | ALDH1A1KMT2APLK1LMNAHPGD | |
| Acetamide SCHEMBL27414047 | 0.66 | ALDH1A1 (0.58) | ALDH1A1PLK1SRCLMNALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575926-A1 | NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES | Almirall Prodesfarma, S.A. (ES) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004058729-A1 | NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES | ALMIRALL PRODESFARMA SA (ES) | 2004-07-15 | — | — | WO | disclosed |