Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.61 |
| ▸ | NPC1 | O15118 | 8/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17197681 | 0.86 | RAB9A (0.50) | RAB9ANPC1HTTATMUSP2 | |
| SCHEMBL30648563 | 0.81 | RAB9A (0.88) | RAB9ANPC1HTTATMKDR | |
| SCHEMBL23566394 | 0.80 | USP2 (0.68) | RAB9ANPC1HTTATMUSP2 | |
| SCHEMBL3820618 | 0.80 | HTT (0.66) | RAB9ANPC1HTTATMKDR | |
| SCHEMBL14439750 | 0.80 | NPC1 (0.61) | RAB9ANPC1HTTATMKDR | |
| SCHEMBL7532358 | 0.80 | KMT2A (0.68) | RAB9ANPC1HTTATMMEN1 | |
| SCHEMBL14252960 | 0.80 | DEGS1 (0.58) | RAB9ANPC1MEN1KMT2ANAMPT | |
| SCHEMBL6174932 | 0.80 | TRPV1 (0.64) | RAB9ANPC1HTTATMMEN1 | |
| SCHEMBL9842635 | 0.79 | RAB9A (0.68) | RAB9ANPC1HTTATMKDR | |
| SCHEMBL29077108 | 0.79 | NPC1 (0.60) | RAB9ANPC1HTTATMKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575918-A2 | SUBSTITUTED BIARYL-4-CARBOXYLIC ACID ARYLAMIDE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2005-09-21 | — | — | EP | claimed |
| WO-2004056774-A2 | SUBSTITUTED BIPHENYL-4-CARBOXYLIC ACID ARYLAMIDE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2004-07-08 | — | — | WO | claimed |
| EP-3362436-B1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIV ANTWERPEN (BE) | 2021-06-30 | — | — | EP | disclosed |
| CN-102030771-B | Compound used as transient receptor potential vanilloid (TRPV1) blocker, medicinal composition and pharmaceutical application thereof | SUN QUN | 2013-07-17 | — | — | CN | disclosed |