SCHEMBL6174699

SCHEMBL6174699

COC(=O)CCC(=O)OC1CC(C)(C)N(OCC(C)(C)O)C(C)(C)C1.COC(=O)CCCCC(=O)OC1CC(C)(C)N(OCC(C)(C)O)C(C)(C)C1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 8/20 0.37
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 5/20 0.34
NAAA Q02083 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
EPHX1 P07099 2/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3950547 0.99 EPHX2 (0.38) EPHX2KMT2AMEN1GAATSHR
SCHEMBL3957275 0.97 EPHX2 (0.39) EPHX2KMT2AMEN1GAATSHR
SCHEMBL3950061 0.96 TSHR (0.39) EPHX2KMT2AMEN1GAATSHR
SCHEMBL3954115 0.96 TSHR (0.35) EPHX2KMT2AMEN1GAATSHR
SCHEMBL38998 0.95 KMT2A (0.38) EPHX2KMT2AMEN1GAATSHR
SCHEMBL524344 0.94 NAAA (0.39) EPHX2KMT2AMEN1GAATSHR
SCHEMBL21582136 0.94 NAAA (0.39) EPHX2KMT2AMEN1GAATSHR
SCHEMBL39302 0.92 KMT2A (0.38) KMT2AMEN1GAATSHRNAAA
SCHEMBL39577 0.92 KMT2A (0.35) KMT2AMEN1GAATSHRSMN1; SMN2
SCHEMBL7692226 0.90 KMT2A (0.35) EPHX2KMT2AMEN1GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1379587-B1 LONG CHAIN HINDERED AMINES AND COMPOSITIONS STABILIZED THEREWITH CIBA SC HOLDING AG (CH) 2005-02-02 EP disclosed
US-6699298-B2 DISCOLORATION INHIBITION CANDLE WAX CIBA SPECIALTY CHEMICALS CORPORATION 2004-03-02 US disclosed
EP-1379587-A1 LONG CHAIN HINDERED AMINES AND COMPOSITIONS STABILIZED THEREWITH Ciba SC Holding AG (CH) 2004-01-14 EP disclosed
US-20030109704-A1 Long chain hindered amines and compositions stabilized therewith WOOD MERVIN G (US) 2003-06-12 US disclosed
WO-2002083781-A1 LONG CHAIN HINDERED AMINES AND COMPOSITIONS STABILIZED THEREWITH CIBA SPECIALTY CHEMICALS HOLDING INC. (US) 2002-10-24 WO disclosed
US-6465645-B1 CONTAINING TRIAZINE GROUPS AND N-ALKYLOXYPIPERIDINE GROUPS; CANDLE WAX WHICH IS EFFECTIVELY STABILIZED AGAINST DISCOLORATION AND FADING CIBA SPECIALTY CHEMICALS CORPORATION 2002-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109704-A1 Long chain hindered amines and compositions stabilized therewith TYR, DDC, AOC2 EPHX2 772/4885KMT2A 3322/4885MEN1 2859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.