Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311776 | 0.82 | APP (0.50) | APPHTR2ALMNAFFAR1IDO1 | |
| SCHEMBL1657799 | 0.82 | APP (0.50) | APPHTR2ALMNAFFAR1IDO1 | |
| SCHEMBL1657802 | 0.82 | APP (0.50) | APPHTR2ALMNAFFAR1IDO1 | |
| SCHEMBL6785416 | 0.79 | HSD17B2 (0.38) | APPFFAR1HSD17B2 | |
| SCHEMBL6785340 | 0.77 | KCNH2 (0.47) | HPGDCYP2C9CYP2C19ALOX15KCNH2 | |
| SCHEMBL6781401 | 0.77 | GRM5 (0.46) | — | |
| SCHEMBL28242920 | 0.77 | APP (0.50) | APPHTR2ALMNAFFAR1NPSR1 | |
| SCHEMBL2799878 | 0.77 | APP (0.44) | APPHTR2ALMNAFFAR1IDO1 | |
| SCHEMBL3031415 | 0.77 | APP (0.55) | APPHTR2ALMNAFFAR1NPSR1 | |
| SCHEMBL19062293 | 0.77 | APP (0.55) | APPHTR2ALMNAFFAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814462-B2 | Functionalized cyclic polymers and methods of preparing same | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20220056167-A1 | Functionalized Cyclic Polymers and Methods of Preparing Same | NATIONAL SCIENCE FOUNDATION | 2022-02-24 | — | — | US | disclosed |
| WO-2020223672-A1 | FUNCTIONALIZED CYCLIC POLYMERS AND METHODS OF PREPARING SAME | UNIVERSITY OF FLORIDA RESEARCHFOUNDATION, INC. (US) | 2020-11-05 | — | — | WO | disclosed |
| EP-2943722-B1 | PROTECTIVE COATING FOR LED LAMP | CREE INC (US) | 2019-08-28 | — | — | EP | disclosed |
| US-10093633-B2 | Functionalized 4- and 5-vinyl substituted regioisomers of 1, 2, 3-triazoles via 1, 3-dipolar cycloaddition and polymers thereof | ISP INVESTMENTS LLC (US) | 2018-10-09 | — | — | US | disclosed |
| EP-2405757-B1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1,2,3-TRIAZOLES VIA 1,3-DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ISP INVESTMENTS INC (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-2807146-B1 | PREPARATION OF [ALPHA]-SULFENYLATED CARBONYL COMPOUNDS FROM PROPARGYLIC ALCOHOLS IN ONE STEP | KAT2BIZ AB (SE) | 2017-09-13 | — | — | EP | disclosed |
| US-9570661-B2 | Protective coating for LED lamp | CREE, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-20160083356-A1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1, 2, 3-TRIAZOLES VIA 1, 3- DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ISP INVESTMENTS INC. (US) | 2016-03-24 | — | — | US | disclosed |
| EP-2943722-A1 | PROTECTIVE COATING FOR LED LAMP | Cree, Inc. (US) | 2015-11-18 | — | — | EP | disclosed |
| EP-2451286-A1 | 4- AND 5 SUBSTITUTED 1,2,3- TRIAZOLE MOIETIES WITH AT LEAST ONE REMOTE POLYMERIZABLE MOIETY AND POLYMERS THEREOF | Isp Investments Inc. (US) | 2012-05-16 | — | — | EP | disclosed |
| US-20120041040-A1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1, 2, 3-TRIAZOLES VIA 1, 3-DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ISP INVESTMENTS INC. (US) | 2012-02-16 | — | — | US | disclosed |
| EP-2405757-A1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1,2,3-TRIAZOLES VIA 1,3-DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | Isp Investments Inc. (US) | 2012-01-18 | — | — | EP | disclosed |
| WO-2011005806-A1 | 4- AND 5 SUBSTITUTED 1,2,3- TRIAZOLE MOIETIES WITH AT LEAST ONE REMOTE POLYMERIZABLE MOIETY AND POLYMERS THEREOF | ISP INVESTMENTS INC. (US) | 2011-01-13 | — | — | WO | disclosed |
| WO-2010104837-A1 | FUNCTIONALIZED 4-AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1,2,3-TRIAZOLES VIA 1,3-DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ISP INVESTMENTS INC. (US) | 2010-09-16 | — | — | WO | disclosed |
| US-7763734-B2 | Synthesis, structure and use of bisoxazolidines for asymmetric catalysis and synthesis | GEORGETOWN UNIVERSITY (US) | 2010-07-27 | — | — | US | disclosed |
| US-4179561-A | REACTING A 3-DIAZOOXINDOLE WITH A SUBSTITUTED ACETYLENE | E. R. SQUIBB & SONS, INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4112096-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4111917-A | POLYURETHANES | W. R. GRACE & CO. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4076818-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1978-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041040-A1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1, 2, 3-TRIAZOLES VIA 1, 3-DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ADH5, ADH1A, ADH1C | APP 4783/4885HTR2A 2690/4885LMNA 4512/4885 |
| US-10093633-B2 | Functionalized 4- and 5-vinyl substituted regioisomers of 1, 2, 3-triazoles via 1, 3-dipolar cycloaddition and polymers thereof | ADH5, ADH1A, ADH1C | APP 4783/4885HTR2A 2690/4885LMNA 4512/4885 |
| US-20160083356-A1 | FUNCTIONALIZED 4- AND 5-VINYL SUBSTITUTED REGIOISOMERS OF 1, 2, 3-TRIAZOLES VIA 1, 3- DIPOLAR CYCLOADDITION AND POLYMERS THEREOF | ADH5, ADH1A, ADH1C | APP 4783/4885HTR2A 2690/4885LMNA 4512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.