Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 9/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6173115 | 0.88 | IGF1R (0.39) | ALDH1A1HSD17B13BRAFMEN1KMT2A | |
| SCHEMBL6172432 | 0.87 | ALDH1A1 (0.38) | ALDH1A1HSD17B13CYP3A4GAACYP2C9 | |
| SCHEMBL6277096 | 0.87 | CYP3A4 (0.43) | ALDH1A1HSD17B13ABL1CYP3A4GAA | |
| SCHEMBL6174981 | 0.87 | CYP3A4 (0.51) | ALDH1A1ABL1CYP3A4GAACYP2C9 | |
| SCHEMBL6177279 | 0.86 | TDP1 (0.42) | ALDH1A1HSD17B13LIPECYP3A4GAA | |
| SCHEMBL6171757 | 0.85 | CYP3A4 (0.41) | ALDH1A1CYP3A4GAACYP2C9CYP2C19 | |
| SCHEMBL6176657 | 0.84 | CYP3A4 (0.40) | ALDH1A1HSD17B13CYP3A4GAACYP2C9 | |
| SCHEMBL6171113 | 0.84 | P2RY1 (0.43) | CYP2C9 | |
| SCHEMBL2942596 | 0.84 | LIPE (0.41) | HSD17B13ABL1LIPEGSK3AGSK3B | |
| SCHEMBL6174447 | 0.83 | ALDH1A1 (0.44) | ALDH1A1HSD17B13CYP3A4GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |