Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175963 | 0.86 | ANO1 (0.48) | ALDH1A1KDM4EUSP2HPGDCYP1A2 | |
| SCHEMBL7834277 | 0.78 | FFAR1 (0.44) | ALDH1A1KDM4EFFAR1MEN1KMT2A | |
| SCHEMBL17506784 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CAMK2ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5205267 | 0.75 | MEN1 (0.41) | ALDH1A1TSHRCAMK2AHTTMEN1 | |
| SCHEMBL2806074 | 0.74 | CYP1A2 (0.59) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4867071 | 0.74 | CAMK2A (0.54) | ALDH1A1KDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL922758 | 0.73 | FFAR1 (0.49) | ALDH1A1CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL25247564 | 0.73 | BCHE (0.67) | ALDH1A1KDM4EFFAR1MEN1KMT2A | |
| SCHEMBL5350074 | 0.72 | PPARG (0.51) | ALDH1A1HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2931410 | 0.72 | MMP13 (0.70) | ALDH1A1KDM4EUSP2HPGDMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |