Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | BAX | Q07812 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17506784 | 0.87 | ALDH1A1 (0.46) | CAMK2ACYP3A4GAAALDH1A1F10 | |
| SCHEMBL10417312 | 0.85 | CYP1A2 (0.62) | CAMK2ALTA4HNR1H2BAXCYP1A2 | |
| SCHEMBL17498442 | 0.83 | CA14 (0.44) | CYP3A4ALDH1A1MAOBTSHRKDM4E | |
| SCHEMBL21633625 | 0.82 | CAMK2A (0.59) | CAMK2ALTA4HNR1H2BAXCYP1A2 | |
| SCHEMBL12474471 | 0.81 | LTA4H (0.57) | LTA4HCYP3A4GAAALDH1A1MAOB | |
| SCHEMBL16542017 | 0.81 | MEN1 (0.51) | LTA4HCYP3A4GAAALDH1A1HSD17B10 | |
| SCHEMBL17506817 | 0.81 | CYP3A4 (0.43) | CAMK2ACYP3A4GAAALDH1A1MAOB | |
| SCHEMBL7774904 | 0.80 | MAOA (0.56) | LTA4HCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5013387 | 0.80 | MAOA (0.56) | LTA4HNR1H2BAXCYP1A2CYP3A4 | |
| SCHEMBL31613229 | 0.80 | MAOA (0.56) | LTA4HCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7364881-B1 | Biological process for the conversion of nitroarenes to ortho-aminophenols using recombinant E. coli strains | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2008-04-29 | — | — | US | claimed |
| US-7364881-B1 | Biological process for the conversion of nitroarenes to ortho-aminophenols using recombinant E. coli strains | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2008-04-29 | — | — | US | disclosed |