Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 16/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175823 | 0.91 | IGF1R (0.39) | IGF1RAR | |
| SCHEMBL6172631 | 0.90 | IGF1R (0.42) | IGF1RARNTRK1ITGAL | |
| SCHEMBL6171604 | 0.90 | IGF1R (0.42) | IGF1RARNTRK1ITGAL | |
| SCHEMBL6175012 | 0.89 | IGF1R (0.45) | IGF1RARNTRK1 | |
| SCHEMBL6176994 | 0.85 | KDM4E (0.40) | IGF1RNTRK1TRPV4 | |
| SCHEMBL6173427 | 0.85 | IGF1R (0.45) | IGF1RARNTRK1 | |
| SCHEMBL6175028 | 0.85 | IGF1R (0.45) | IGF1RARNTRK1 | |
| SCHEMBL6174258 | 0.84 | IGF1R (0.49) | IGF1RARITGAL | |
| Trifluoroacetic Acid SCHEMBL17558379 | 0.83 | IGF1R (0.42) | IGF1RARNTRK1 | |
| SCHEMBL2941978 | 0.79 | IGF1R (0.62) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |