SCHEMBL6176

SCHEMBL6176

[c]1ccc(-c2nnn[nH]2)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27513088 0.96
SCHEMBL2028396 0.84 ADH5 (0.32)
SCHEMBL13411813 0.81 ADH5 (0.36)
SCHEMBL4712959 0.81 DCUN1D1 (0.36)
Water SCHEMBL7382263 0.80 NR1H2 (0.42)
SCHEMBL7429132 0.79 ESR1 (0.32)
SCHEMBL7446017 0.79 ESR1 (0.32)
SCHEMBL7430711 0.77 RPS6KA3 (0.39)
SCHEMBL4950 0.77 NR1H2 (0.43)
SCHEMBL392763 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1086 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240132531-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2024-04-25 US claimed
US-20230416205-A1 COMPOUNDS, COMPOSITIONS, AND METHODS TENVIE THERAPEUTICS, INC. 2023-12-28 US claimed
CN-117043156-A Novel galectin inhibitors of galectins 格莱克特生物技术公司 2023-11-10 CN claimed
EP-4267570-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS Galecto Biotech AB (DK) 2023-11-01 EP claimed
EP-4267568-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS Galecto Biotech AB (DK) 2023-11-01 EP claimed
EP-4247376-A1 COMPOUNDS, COMPOSITIONS, AND METHODS Denali Therapeutics Inc. (US) 2023-09-27 EP claimed
CN-116710447-A Novel galectin inhibitors of galectins 格莱克特生物技术公司 2023-09-05 CN claimed
CN-116507608-A Compounds, compositions, and methods 戴纳立制药公司 2023-07-28 CN claimed
WO-2023122587-A2 TRIPEPTIDE LINKERS AND METHODS OF USE THEREOF THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-06-29 WO claimed
WO-2023118267-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2023-06-29 WO claimed
WO-1994023577-A1 TRIAZOLYL AND TETRAZOLYL PHENYL SUBSTITUTED CARBAPENEM COMPOUNDS MERCK & CO., INC. (US) 1994-10-27 WO claimed
CN-1093705-A 1 of new diaryl replacement, 3-oxygen thia-1, the 3-dithia-and 1, the synthetic and application in treatment of 3-two oxa-s penta ring INNOVATIVE TECH CENTER (US) 1994-10-19 CN claimed
US-5350746-A Antibiotics MERCK & CO., INC. (US) 1994-09-27 US claimed
EP-0589665-A2 4,5,6,7-Tetrahydro-1H-imidazo 4,5-c pyridine-6-carboxylic acid amide derivatives as angiotensine II antagonistes KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1994-03-30 EP claimed
US-5268377-A Imidazoindolizine derivatives process for preparation thereof and use thereof to treat hypertension TANABE SEIYAKU CO., LTD. (JP) 1993-12-07 US claimed
US-5225559-A DIARYLMETHOXYPIPERIDINE DERIVATIVES UBE INDUSTRIES, LTD. (JP) 1993-07-06 US claimed
CN-1070913-A Imidazo indolizine derivative and preparation method thereof TANABE SEIYAKU CO (JP) 1993-04-14 CN claimed
EP-0531876-A2 Imidazoindolizine derivatives and process for preparation thereof TANABE SEIYAKU CO., LTD. (JP) 1993-03-17 EP claimed
EP-0485984-A2 Diarylmethoxypiperidine derivatives UBE INDUSTRIES, LTD. (JP) 1992-05-20 EP claimed
CN-86108626-A Phenylformic acid and benzoate derivatives with anti-inflammatory and pain palliation efficacy 1987-07-22 CN claimed