SCHEMBL2028396

SCHEMBL2028396

c1cc(-c2nnn[nH]2)ccc1-c1nnn[nH]1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADH5 P11766 1/20 0.32
ALPL P05186 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13411813 0.97 ADH5 (0.36) ADH5
SCHEMBL17254440 0.91 ESR1 (0.33) ADH5
SCHEMBL5046599 0.89 METAP2 (0.35)
SCHEMBL6505461 0.89 NR1H2 (0.41)
SCHEMBL1875818 0.89
SCHEMBL4950 0.87 NR1H2 (0.43)
SCHEMBL23488248 0.87 KDM4E (0.31) ADH5
Water SCHEMBL7382263 0.85 NR1H2 (0.42)
SCHEMBL22498864 0.85 NR1H2 (0.42)
SCHEMBL703646 0.85 LMNA (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060168-A High-temperature-resistant fluorosilicone rubber and vulcanization preparation method thereof 广东阿普邦新材料科技股份有限公司 2026-05-19 CN claimed
CN-111943898-A Benzotetrazole derivatives, preparation method thereof, pharmaceutical composition containing same and application thereof 浙江大学 2020-11-17 CN claimed
EP-2519467-A1 MODULAR BIOCOMPATIBLE MATERIALS FOR MEDICAL DEVICES AND USES THEREOF Colorado State University Research Foundation (US) 2012-11-07 EP claimed
WO-2011082164-A1 MODULAR BIOCOMPATIBLE MATERIALS FOR MEDICAL DEVICES AND USES THEREOF COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-07-07 WO claimed
US-20110159116-A1 BIOCOMPATIBLE MATERIALS FOR MEDICAL DEVICES COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-06-30 US claimed
CN-122060168-A High-temperature-resistant fluorosilicone rubber and vulcanization preparation method thereof 广东阿普邦新材料科技股份有限公司 2026-05-19 CN disclosed
EP-4722199-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2026-04-08 EP disclosed
WO-2025047447-A1 TETRAZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID TETRAZOLE COMPOUND, AND USE THEREOF 四国化成工業株式会社 2025-03-06 WO disclosed
WO-2024247919-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF 四国化成工業株式会社 2024-12-05 WO disclosed
EP-3302789-B1 SEPARATION OF METAL-ORGANIC FRAMEWORKS COMMW SCIENT IND RES ORG (AU) 2022-06-08 EP disclosed
US-10906023-B2 Production of metal-organic frameworks COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION 2021-02-02 US disclosed
CN-111943898-A Benzotetrazole derivatives, preparation method thereof, pharmaceutical composition containing same and application thereof 浙江大学 2020-11-17 CN disclosed
US-8500889-B2 Gas adsorption material COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2013-08-06 US disclosed
WO-2011133999-A1 CRYSTALLISATION FACILITATORS FOR THE SYNTHESIS OF METAL ORGANIC FRAMEWORKS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2011-11-03 WO disclosed
US-20110159116-A1 BIOCOMPATIBLE MATERIALS FOR MEDICAL DEVICES COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-06-30 US disclosed
US-7857985-B2 Metal-polishing liquid and chemical mechanical polishing method using the same FUJIFILM CORPORATION (JP) 2010-12-28 US disclosed
US-7857985-B2 Metal-polishing liquid and chemical mechanical polishing method using the same FUJIFILM CORPORATION (JP) 2010-12-28 US disclosed
WO-2010075610-A1 GAS ADSORPTION MATERIAL COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-07-08 WO disclosed
US-20070186484-A1 Metal-polishing liquid and chemical mechanical polishing method using the same FUJIFILM CORPORATION (JP) 2007-08-16 US disclosed
US-20070186484-A1 Metal-polishing liquid and chemical mechanical polishing method using the same FUJIFILM CORPORATION (JP) 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10906023-B2 Production of metal-organic frameworks OAT, CYP4F2, OSTC ADH5 1360/4885ALPL 673/4885
US-20110159116-A1 BIOCOMPATIBLE MATERIALS FOR MEDICAL DEVICES NOS2, NOS3, NOS1 ADH5 3291/4885ALPL 2593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.