Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.55 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28424508 | 0.87 | MAPT (0.64) | CSNK2A2CSNK2BCSNK2A1CSNK2A3TTR | |
| SCHEMBL30175553 | 0.85 | MAPT (0.62) | CSNK2A2CSNK2BCSNK2A1CSNK2A3TTR | |
| SCHEMBL6176954 | 0.83 | KDM4E (0.68) | TTRMAPTKDM4EMEN1CYP3A4 | |
| SCHEMBL25229668 | 0.75 | CSNK2A2 (0.61) | CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT | |
| SCHEMBL68189 | 0.73 | TTR (0.83) | TTRMAPTKDM4EMEN1KMT2A | |
| SCHEMBL11439145 | 0.73 | TTR (0.59) | CSNK2A2CSNK2BCSNK2A1TTRMAPT | |
| SCHEMBL17786624 | 0.72 | MAPT (0.52) | CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT | |
| SCHEMBL25239618 | 0.72 | CYP1A2 (0.54) | CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT | |
| SCHEMBL17940164 | 0.72 | KDM4E (0.56) | CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT | |
| Hydrochloric Acid SCHEMBL11749391 | 0.71 | TTR (0.81) | TTRMAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834510-B1 | Flavone derivative and medicine comprising the same | KOWA CO (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6136848-A | ANTIALLERGENS; ASTHMA THERAPY | KOWA CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0834510-A2 | Flavone derivative and medicine comprising the same | KOWA CO. LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |