SCHEMBL617626

SCHEMBL617626

N#Cc1ccc(C/C(=N/N(C(N)=O)c2ccc(OC(F)(F)F)cc2)c2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
VNN1 O95497 3/20 0.42
SERPINE1 P05121 2/20 0.41
MAOB P27338 1/20 0.38
P2RY1 P47900 2/20 0.38
CCR2 P41597 3/20 0.37
MRGPRX4 Q96LA9 2/20 0.36
RORC P51449 1/20 0.36
HTR2C P28335 1/20 0.36
ITK Q08881 1/20 0.35
ABL1 P00519 1/20 0.35
NLRP3 Q96P20 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1121810 0.91 SERPINE1 (0.37) VNN1SERPINE1MAOBMRGPRX4HTR2C
SCHEMBL20550255 0.90 VNN1 (0.41) VNN1MAOBP2RY1CCR2MRGPRX4
SCHEMBL16166139 0.90 VNN1 (0.41) VNN1MAOBP2RY1CCR2MRGPRX4
SCHEMBL9018845 0.82 VNN1 (0.39) VNN1MAOBMRGPRX4RORC
SCHEMBL8383717 0.82 SERPINE1 (0.43) VNN1SERPINE1MAOBP2RY1CCR2
SCHEMBL8858575 0.79 KMT2A (0.39) SERPINE1MRGPRX4ITKABL1
SCHEMBL617627 0.78 P2RY1 (0.49) VNN1P2RY1ABL1NLRP3
SCHEMBL1117478 0.78 P2RY1 (0.49) VNN1P2RY1ABL1NLRP3
SCHEMBL27082 0.78 P2RY1 (0.49) VNN1P2RY1ABL1NLRP3
SCHEMBL29364764 0.78 P2RY1 (0.49) VNN1P2RY1ABL1NLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9504253-B2 Liquid pesticide composition containing N-phenylsemicarbazone pesticide compounds BASF SE (DE) 2016-11-29 US claimed
EP-2061323-B1 LIQUID PESTICIDE COMPOSITION CONTAINING N-PHENYLSEMICARBAZONE PESTICIDE COMPOUNDS BASF SE (DE) 2016-06-29 EP claimed
US-7906130-B2 Amitraz compositions WYETH LLC (US) 2011-03-15 US claimed
US-20100093532-A1 Pesticidal Mixtures Comprising Phenylsemicarbazone and Clothianidin BASF SE (DE) 2010-04-15 US claimed
US-20090317433-A1 Liquid Pesticide Composition Containing N-Phenylsemicarbazone Pesticide Compounds BASF SE (DE) 2009-12-24 US claimed
EP-2109365-A2 PESTICIDAL MIXTURES COMPRISING PHENYLSEMICARBAZONE AND CLOTHIANIDIN BASF SE (DE) 2009-10-21 EP claimed
EP-2061323-A2 LIQUID PESTICIDE COMPOSITION CONTAINING N-PHENYLSEMICARBAZONE PESTICIDE COMPOUNDS BASF SE (DE) 2009-05-27 EP claimed
WO-2008095870-A2 PESTICIDAL MIXTURES COMPRISING PHENYLSEMICARBAZONE AND CLOTHIANIDIN BASF SE (DE) 2008-08-14 WO claimed
WO-2008040727-A2 LIQUID PESTICIDE COMPOSITION CONTAINING N-PHENYLSEMICARBAZONE PESTICIDE COMPOUNDS BASF SE (DE) 2008-04-10 WO claimed
US-9504253-B2 Liquid pesticide composition containing N-phenylsemicarbazone pesticide compounds BASF SE (DE) 2016-11-29 US disclosed
EP-2061323-B1 LIQUID PESTICIDE COMPOSITION CONTAINING N-PHENYLSEMICARBAZONE PESTICIDE COMPOUNDS BASF SE (DE) 2016-06-29 EP disclosed
EP-1973401-B1 SOLVENT MIXTURE FOR PREPARING WATER-DILUTABLE LIQUID CONCENTRATE FORMULATION OF ORGANIC PESTICIDE COMPOUNDS BASF SE (DE) 2014-07-02 EP disclosed
EP-2398318-B1 IMPROVED-SCENT ECTOPARASITICIDAL FORMULATION WYETH LLC (US) 2012-12-05 EP disclosed
US-20120041042-A1 Scent Ectoparasiticidal Formulation WYETH LLC (US) 2012-02-16 US disclosed
US-20080194642-A1 HIGH DOSE, LONG-ACTING ECTOPARASITICIDE FOR EXTENDED CONTROL WYETH (US) 2008-08-14 US disclosed
WO-2008040727-A2 LIQUID PESTICIDE COMPOSITION CONTAINING N-PHENYLSEMICARBAZONE PESTICIDE COMPOUNDS BASF SE (DE) 2008-04-10 WO disclosed
EP-1895847-A2 USE OF PHENYLSEMICARBAZONES FOR SEED TREATMENT BASF SE (DE) 2008-03-12 EP disclosed
WO-2007077246-A2 SOLVENT MIXTURE FOR PREPARING WATER-DILUTABLE LIQUID CONCENTRATE FORMULATION OF ORGANIC PESTICIDE COMPOUNDS BASF SE (DE) 2007-07-12 WO disclosed
WO-2006133928-A2 USE OF PHENYLSEMICARBAZONES FOR SEED TREATMENT BASF AKTIENGESELLSCHAFT (DE) 2006-12-21 WO disclosed
EP-0462456-B1 Hydrazinecarboxamide derivatives, a process for production thereof, and uses thereof NIHON NOHYAKU CO LTD (JP) 1996-05-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090317433-A1 Liquid Pesticide Composition Containing N-Phenylsemicarbazone Pesticide Compounds CNPY3, CNPY2, C1S VNN1 2034/4885SERPINE1 3982/4885MAOB 1437/4885
US-20100093532-A1 Pesticidal Mixtures Comprising Phenylsemicarbazone and Clothianidin DDT, C9, CNPY3 VNN1 588/4885SERPINE1 4081/4885MAOB 1146/4885
US-20080194642-A1 HIGH DOSE, LONG-ACTING ECTOPARASITICIDE FOR EXTENDED CONTROL KIT, VEGFA, IL5 VNN1 842/4885SERPINE1 527/4885MAOB 899/4885
US-20120041042-A1 Scent Ectoparasiticidal Formulation IL5, CCL11, CYP3A5 VNN1 1115/4885SERPINE1 790/4885MAOB 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.