SCHEMBL9018845

SCHEMBL9018845

N#Cc1ccc(C/C(=N/N(C(N)=O)c2ccc(C(F)(F)F)cc2)c2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VNN1 O95497 2/20 0.39
RXRA P19793 1/20 0.39
RXRG P48443 1/20 0.39
RORC P51449 2/20 0.37
CTBP2 P56545 1/20 0.37
KIF11 P52732 1/20 0.36
MLYCD O95822 1/20 0.36
CXCR3 P49682 1/20 0.36
NPC1 O15118 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
GRIN2B Q13224 1/20 0.36
PDPK1 O15530 1/20 0.35
TMEM97 Q5BJF2 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
MAOB P27338 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
MRGPRX4 Q96LA9 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL617626 0.82 VNN1 (0.42) VNN1RORCMAOBMRGPRX4
SCHEMBL9018901 0.82 PAX8 (0.42) VNN1GRIN2BMAOB
SCHEMBL16166139 0.81 VNN1 (0.41) VNN1RXRARXRGRORCMEN1
SCHEMBL20550255 0.81 VNN1 (0.41) VNN1RXRARXRGRORCMEN1
SCHEMBL9508158 0.80 GRIN2B (0.47) MEN1KMT2AGRIN2BMRGPRX4SMN1; SMN2
SCHEMBL9018830 0.77 CTSL (0.48) CTBP2GRIN2BSMN1; SMN2L3MBTL1
SCHEMBL8858575 0.76 KMT2A (0.39) MLYCDKMT2AGRIN2BMRGPRX4
SCHEMBL9018847 0.74 SAE1 (0.49) VNN1RORCMLYCDNPC1MEN1
SCHEMBL9018882 0.74 L3MBTL1 (0.47) NPC1MEN1KMT2AGRIN2BRAB9A
SCHEMBL9018853 0.74 BCL2A1 (0.39) MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5543573-A INSECTICIDES NIHON NOHYAKU CO., LTD. (JP) 1996-08-06 US disclosed
EP-0462456-B1 Hydrazinecarboxamide derivatives, a process for production thereof, and uses thereof NIHON NOHYAKU CO LTD (JP) 1996-05-08 EP disclosed
EP-0462456-A1 Hydrazinecarboxamide derivatives, a process for production thereof, and uses thereof NIHON NOHYAKU CO., LTD. (JP) 1991-12-27 EP disclosed