Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175375 | 0.77 | KMT2A (0.44) | CASP1NCEH1L3MBTL1KMT2ATSHR | |
| SCHEMBL29669502 | 0.67 | KDM4E (0.67) | CASP1KMT2ATSHRMEN1KDM4E | |
| SCHEMBL6179565 | 0.67 | ALDH1A1 (0.49) | CASP1NCEH1KMT2ATSHRKDM4E | |
| SCHEMBL350989 | 0.67 | KDM4E (0.67) | CASP1KMT2ATSHRMEN1KDM4E | |
| SCHEMBL27598989 | 0.66 | ACP3 (0.44) | ACP3NCEH1L3MBTL1KMT2ATSHR | |
| SCHEMBL29672837 | 0.66 | KDM4E (0.47) | CASP1NCEH1KMT2ATSHRKDM4E | |
| SCHEMBL2986084 | 0.66 | KDM4E (0.47) | CASP1NCEH1KMT2ATSHRMEN1 | |
| SCHEMBL4456627 | 0.66 | KDM4E (0.47) | CASP1NCEH1KMT2ATSHRKDM4E | |
| SCHEMBL11043768 | 0.65 | CASP1 (0.41) | CASP1NCEH1KMT2ATSHRMEN1 | |
| SCHEMBL27598994 | 0.65 | ACP3 (0.43) | ACP3NCEH1L3MBTL1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392280-A4 | ARYLSULFONAMIDE ETHERS, AND METHODS OF USE THEREOF | WARNER LAMBERT CO (US) | 2005-11-30 | — | — | EP | disclosed |
| EP-1392280-A2 | ARYLSULFONAMIDE ETHERS, AND METHODS OF USE THEREOF | Abbott GmbH & Co. KG (DE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002089749-A2 | ARYLSULFONAMIDE ETHERS, AND METHODS OF USE THEREOF | ABBOTT GMBH & CO.KG (DE) | 2002-11-14 | — | — | WO | disclosed |