Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 4/20 | 0.33 |
| ▸ | LIPE | Q05469 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.32 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.32 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.32 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.32 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.32 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.32 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.32 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175578 | 0.88 | LMNA (0.42) | LMNAPOLBL3MBTL1HRH4MCHR1 | |
| SCHEMBL6173438 | 0.88 | LMNA (0.42) | LMNAPOLBL3MBTL1HRH4MCHR1 | |
| SCHEMBL6175660 | 0.86 | LMNA (0.40) | LMNAPOLBL3MBTL1HRH4MCHR1 | |
| SCHEMBL6172084 | 0.86 | LMNA (0.40) | LMNAPOLBL3MBTL1HRH4MCHR1 | |
| SCHEMBL6171053 | 0.85 | LMNA (0.40) | LMNAPOLBL3MBTL1HRH4MCHR1 | |
| SCHEMBL6177038 | 0.85 | LMNA (0.42) | LMNAPOLBL3MBTL1MCHR1PDE2A | |
| SCHEMBL6174848 | 0.85 | LMNA (0.46) | LMNAPOLBL3MBTL1PDE2ALIPE | |
| SCHEMBL6171614 | 0.84 | LMNA (0.39) | LMNAPOLBL3MBTL1HRH4MCHR1 | |
| SCHEMBL6171105 | 0.84 | LMNA (0.39) | LMNAPOLBL3MBTL1LIPEATP1A1 | |
| SCHEMBL6174756 | 0.84 | MAT2A (0.43) | LMNAPOLBL3MBTL1MCHR1NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |