SCHEMBL6176844

SCHEMBL6176844

C#CCc1cccc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.52
CYP2C19 P33261 2/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2D6 P10635 2/20 0.48
TDP1 Q9NUW8 2/20 0.47
CA2 P00918 1/20 0.46
ACP3 P15309 1/20 0.46
NQO2 P16083 1/20 0.43
CYP2A6 P11509 2/20 0.43
HPGD P15428 2/20 0.42
ALDH1A1 P00352 2/20 0.42
HTT P42858 1/20 0.42
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
PTGS2 P35354 1/20 0.41
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL28996502 0.91 TDP1 (0.58) CYP1A2CYP2C19CYP2C9TDP1CA2
SCHEMBL6180488 0.86 CYP1A2 (0.41) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL2858430 0.82 CYP1A2 (0.56) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL2858432 0.82 CYP1A2 (0.56) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL17540875 0.82 ALDH1A1 (0.38) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL28097582 0.79 CYP1A2 (0.48) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL1611986 0.78 CYP1A2 (0.52) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL7033804 0.78 CYP1A2 (0.57) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL182660 0.78 CYP1A2 (0.52) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL146603 0.78 CYP1A2 (0.52) CYP1A2CYP2C19CYP2C9CYP2D6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0153261-B1 ESTERS FROM THE FAMILY OF THE N-PHOSPHONOMETHYLGLYCINE AND THEIR USE FOR THE PREPARATION OF KNOWN HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1989-01-25 EP claimed
EP-3416730-B1 DERMATOLOGICAL COSMETIC COMPOSITION COMPRISING AN SDKP PEPTIDE OR AN ANALOG THEREOF RPM DERMATOLOGIE (FR) 2021-07-07 EP disclosed
EP-3416730-A1 DERMATOLOGICAL COSMETIC COMPOSITION COMPRISING AN SDKP PEPTIDE OR AN ANALOG THEREOF RPM Dermatologie (FR) 2018-12-26 EP disclosed
CN-108530365-A 1,4- naphthoquinones/anthraquinone imdazole derivatives and its preparation and use 上海交通大学 2018-09-14 CN disclosed
WO-2017140997-A1 DERMATOLOGICAL COSMETIC COMPOSITION COMPRISING AN SDKP PEPTIDE OR AN ANALOG THEREOF RPM DERMATOLOGIE (FR) 2017-08-24 WO disclosed
EP-1392280-A4 ARYLSULFONAMIDE ETHERS, AND METHODS OF USE THEREOF WARNER LAMBERT CO (US) 2005-11-30 EP disclosed
EP-1392280-A2 ARYLSULFONAMIDE ETHERS, AND METHODS OF USE THEREOF Abbott GmbH & Co. KG (DE) 2004-03-03 EP disclosed
WO-2002089749-A2 ARYLSULFONAMIDE ETHERS, AND METHODS OF USE THEREOF ABBOTT GMBH & CO.KG (DE) 2002-11-14 WO disclosed
EP-0135454-B1 HERBICIDES OF THE SULFON IMIDE-TYPE WITH AN AMINOMETHYLPHOSPHONIC GROUP RHONE-POULENC AGROCHIMIE (FR) 1989-05-31 EP disclosed
EP-0153261-B1 ESTERS FROM THE FAMILY OF THE N-PHOSPHONOMETHYLGLYCINE AND THEIR USE FOR THE PREPARATION OF KNOWN HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1989-01-25 EP disclosed
EP-0189358-B1 N-(PHOSPHONOMETHYLGLYCYL) SULFONYL AMINE-TYPE HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1988-09-28 EP disclosed
US-4767797-A Photocurable compositions of poly(ethynylphenyl)acetylene, its copolymer and composition thereof ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-08-30 US disclosed
EP-0272508-A2 Herbicides of the sulfonimide type with an aminomethyl phosphonic group RHONE-POULENC AGROCHIMIE (FR) 1988-06-29 EP disclosed
EP-0189358-A1 N-(phosphonomethylglycyl) sulfonyl amine-type herbicides RHONE-POULENC AGROCHIMIE (FR) 1986-07-30 EP disclosed
EP-0153261-A1 Esters from the family of the N-phosphonomethylglycine and their use for the preparation of known herbicides RHONE-POULENC AGROCHIMIE (FR) 1985-08-28 EP disclosed
EP-0135454-A1 Herbicides of the sulfon imide-type with an aminomethylphosphonic group RHONE-POULENC AGROCHIMIE (FR) 1985-03-27 EP disclosed