⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013775 | 0.77 | — | — | |
| SCHEMBL3023 | 0.71 | — | — | |
| SCHEMBL13132093 | 0.71 | — | — | |
| SCHEMBL28182083 | 0.71 | ALDH1A1 (0.34) | — | |
| SCHEMBL8420894 | 0.71 | — | — | |
| SCHEMBL1408772 | 0.67 | ALDH1A1 (0.37) | — | |
| SCHEMBL8252306 | 0.67 | CHRM2 (0.33) | — | |
| Clorethate SCHEMBL41346 | 0.67 | CHRM2 (0.39) | — | |
| SCHEMBL9230930 | 0.67 | ALDH1A1 (0.34) | — | |
| SCHEMBL19514706 | 0.66 | CHRM2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200411-B1 | PROCESS FOR SYNTHESIS OF HETEROARYL-SUBSTITUTED UREA COMPOUNDS | BOEHRINGER INGELHEIM PHARMA (US) | 2005-12-14 | — | — | EP | disclosed |
| US-6894173-B2 | Intermediates useful for synthesis of heteroaryl-substituted urea compounds, and processes of making same | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-05-17 | — | — | US | disclosed |
| US-6835832-B2 | Catalytic hydrogenation | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-12-28 | — | — | US | disclosed |
| US-6774233-B2 | AUTOIMMUNE DISEASE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-08-10 | — | — | US | disclosed |
| US-6753426-B2 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-06-22 | — | — | US | disclosed |
| US-20030181718-A1 | A chemical intermediate carbamate compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-09-25 | — | — | US | disclosed |
| US-20030166930-A1 | Process for synthesis of heteroaryl-substituted urea compounds useful as antiinflammatory agents | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-09-04 | — | — | US | disclosed |
| US-20030166931-A1 | Process for synthesis of heteroaryl-substituted urea compounds useful as antiinflammatory agents | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-09-04 | — | — | US | disclosed |
| US-6583282-B1 | Formation of a urea by reacting an aromatic carbamate with a aromatic amine | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-06-24 | — | — | US | disclosed |
| US-20030109703-A1 | Polymorph and process for preparing same | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-06-12 | — | — | US | disclosed |
| EP-1200411-A2 | NOVEL PROCESS FOR SYNTHESIS OF HETEROARYL-SUBSTITUTED UREA COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001004115-A2 | NOVEL PROCESS FOR SYNTHESIS OF HETEROARYL-SUBSTITUTED UREA COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-01-18 | — | — | WO | disclosed |
| US-4897416-A | 5-OXIMINO-13B-CARBONYLTHIOMILBEMYCIN DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1990-01-30 | — | — | US | disclosed |
| US-4859657-A | Pesticides | CIBA-GEIGY CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |
| US-4003909-A | [(1,2,4-Oxadiazol-3-yl)phenyl]carbamic or thiocarbamic acid esters | E. R. SQUIBB & SONS, INC. (US) | 1977-01-18 | — | — | US | disclosed |
| US-3978078-A | Process for the preparation of ampicillin | RHONE-POULENC S.A. (FR) | 1976-08-31 | — | — | US | disclosed |