Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175964 | 0.95 | KDM4E (0.36) | KDM4ELMNAMAPTHPGDTSHR | |
| SCHEMBL6178480 | 0.77 | MEN1 (0.39) | KDM4ELMNAHPGDTSHR | |
| SCHEMBL4873844 | 0.76 | ALDH1A1 (0.38) | KDM4ELMNAMAPTHPGDTSHR | |
| SCHEMBL7128136 | 0.74 | ALDH1A1 (0.42) | KDM4E | |
| SCHEMBL4878997 | 0.72 | HTR1A (0.34) | MAPT | |
| SCHEMBL4877091 | 0.72 | HTR1A (0.35) | HRH3 | |
| SCHEMBL4876974 | 0.72 | KMT2A (0.42) | KDM4ELMNAHPGDTSHRHTT | |
| SCHEMBL7125197 | 0.72 | HRH1 (0.40) | KDM4ETSHRHTTHRH3 | |
| SCHEMBL4876361 | 0.72 | KDM4E (0.38) | KDM4ELMNAMAPTHPGDHTT | |
| SCHEMBL4878132 | 0.71 | ALDH1A1 (0.34) | KDM4EMAPTHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399438-B1 | NOVEL HETEROARYL DERIVATIVES, THEIR PREPARATION AND USE | LUNDBECK & CO AS H (DK) | 2005-12-07 | — | — | EP | claimed |