SCHEMBL617828

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10189449	0.94	SMN1; SMN2 (0.37)	RXFP1ADORA3ADORA2BCYP3A4CYP2C19
	SCHEMBL12118594	0.92	MAPT (0.41)	RXFP1ADORA3ADORA2BPOLBMEN1
	SCHEMBL10189450	0.87	ALDH1A1 (0.39)	RXFP1ADORA3ADORA2BPOLBMAPT
	SCHEMBL615760	0.86	POLB (0.43)	RXFP1CYP3A4CYP2C19POLBMEN1
	SCHEMBL618841	0.85	ADORA3 (0.48)	RXFP1ADORA3ADORA2BCYP3A4CYP2C19
	SCHEMBL4700326	0.84	HTT (0.50)	RXFP1ADORA3ADORA2BCYP3A4CYP2C19
	SCHEMBL3303324	0.83	MEN1 (0.41)	RXFP1ADORA3ADORA2BCYP3A4CYP2C19
	SCHEMBL1167737	0.83	MAPT (0.41)	RXFP1CYP3A4CYP2C19MEN1KMT2A
	SCHEMBL12118580	0.82	NPSR1 (0.50)	RXFP1CYP3A4CYP2C19POLBMEN1
	Hydrochloric Acid SCHEMBL618361	0.82	MEN1 (0.41)	RXFP1ADORA3ADORA2BPOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.