SCHEMBL617862

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL615782	0.87	HSP90AA1 (0.44)	PTGS2ALDH1A1KDM4EMEN1MAPT
	SCHEMBL617871	0.84	ALDH1A1 (0.40)	PTGS2ALDH1A1KDM4EMEN1MAPT
	SCHEMBL10188998	0.83	AHR (0.46)	PTGS2ALDH1A1KDM4EMEN1MAPT
	SCHEMBL616535	0.83	PTGS2 (0.40)	PTGS2ALDH1A1KDM4EMEN1MAPT
	SCHEMBL615988	0.83	PTGS2 (0.42)	PTGS2ALDH1A1KDM4EMEN1MAPT
	SCHEMBL616903	0.83	PTGS2 (0.40)	PTGS2ALDH1A1KDM4EMEN1MAPT
	SCHEMBL616131	0.82	ALDH1A1 (0.40)	PTGS2ALDH1A1KDM4EMEN1MAPT
	Hydrochloric Acid SCHEMBL616255	0.82	AHR (0.45)	ALDH1A1KDM4EMEN1MAPTHPGD
	SCHEMBL617990	0.82	TSHR (0.39)	PTGS2ALDH1A1KDM4EMEN1MAPT
	SCHEMBL618669	0.81	PTGS2 (0.38)	PTGS2ALDH1A1KDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.