SCHEMBL6179599

SCHEMBL6179599

CCCCN1CCC(CNC(=O)c2cc(Cl)cn3cc(CC)nc23)CC1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.48
HTR4 Q13639 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6175694 0.91 NR4A2 (0.49) NR4A2HTR4
SCHEMBL6176072 0.90 KCNH2 (0.52) NR4A2HTR4
SCHEMBL7348053 0.84 HTR3A (0.51) HTR4
SCHEMBL6767167 0.83 KCNH2 (0.62) NR4A2HTR4
SCHEMBL6761915 0.78 HTR4 (0.49) NR4A2HTR4
SCHEMBL6179088 0.78 KCNH2 (0.62) NR4A2HTR4
SCHEMBL6180780 0.76 KCNH2 (0.60) HTR4
SCHEMBL6761922 0.75 KCNH2 (0.64) NR4A2HTR4
Hydrochloric Acid SCHEMBL6770784 0.75 KCNH2 (0.59) HTR4
SCHEMBL7353765 0.75 NR4A2 (0.51) NR4A2HTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1440071-B1 IMIDAZOPYRIDINE COMPOUNDS AS 5-HT 4? RECEPTOR MODULATORS PFIZER (US) 2005-10-26 EP disclosed