Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 15/20 | 0.46 |
| ▸ | FNTB | P49356 | 15/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 10/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178568 | 0.84 | FNTA (0.42) | FNTAFNTB | |
| SCHEMBL6180669 | 0.83 | FNTA (0.46) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7679202 | 0.82 | FNTA (0.48) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8100058 | 0.80 | CYP11B1 (0.53) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8444284 | 0.80 | CYP11B1 (0.53) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL8095228 | 0.79 | CYP11B1 (0.52) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL8421807 | 0.79 | CYP11B1 (0.52) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6178566 | 0.78 | FNTA (0.42) | FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL7682279 | 0.76 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL8531142 | 0.76 | CYP11B1 (0.59) | FNTAFNTBPGGT1BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140909-B1 | NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | SCHERING CORP (US) | 2005-07-06 | — | — | EP | disclosed |
| US-6432959-B1 | ANTITUMOR AGENTS | SCHERING CORPORATION | 2002-08-13 | — | — | US | disclosed |
| EP-1140909-A1 | NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039119-A1 | NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |