Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 16/20 | 0.48 |
| ▸ | FNTB | P49356 | 16/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 12/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.45 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180669 | 0.85 | FNTA (0.46) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL6003187 | 0.84 | FNTA (0.55) | FNTAFNTBPGGT1BALDH1A1KCNH2 | |
| SCHEMBL8436859 | 0.84 | FNTA (0.55) | FNTAFNTBPGGT1BALDH1A1KCNH2 | |
| SCHEMBL6179814 | 0.82 | FNTA (0.46) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7682279 | 0.80 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL4459587 | 0.78 | FNTA (0.53) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7682332 | 0.77 | FNTA (0.47) | FNTAFNTBALDH1A1EPHX2 | |
| SCHEMBL5298259 | 0.77 | FNTA (0.51) | FNTAFNTBPGGT1BALDH1A1KCNH2 | |
| SCHEMBL8434426 | 0.77 | FNTA (0.51) | FNTAFNTBPGGT1BALDH1A1KCNH2 | |
| SCHEMBL7679247 | 0.76 | FNTA (0.50) | FNTAFNTBPGGT1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432959-B1 | ANTITUMOR AGENTS | SCHERING CORPORATION | 2002-08-13 | — | — | US | disclosed |
| EP-1140909-A1 | NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039119-A1 | NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |