Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.49 |
| ▸ | FNTB | P49356 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 2/20 | 0.46 |
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682332 | 0.91 | FNTA (0.47) | FNTAFNTBPOLBMC4R | |
| SCHEMBL7679202 | 0.80 | FNTA (0.48) | FNTAFNTB | |
| SCHEMBL6180669 | 0.79 | FNTA (0.46) | FNTAFNTB | |
| SCHEMBL7679247 | 0.78 | FNTA (0.50) | FNTAFNTB | |
| SCHEMBL6178568 | 0.76 | FNTA (0.42) | FNTAFNTBPOLBMC4R | |
| SCHEMBL6179814 | 0.76 | FNTA (0.46) | FNTAFNTB | |
| SCHEMBL7681229 | 0.73 | FNTA (0.48) | FNTAFNTB | |
| SCHEMBL7673415 | 0.72 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL8095394 | 0.71 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL4409108 | 0.71 | MMP1 (0.49) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432959-B1 | ANTITUMOR AGENTS | SCHERING CORPORATION | 2002-08-13 | — | — | US | disclosed |
| EP-1140909-A1 | NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039119-A1 | NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |