Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178568 | 0.84 | FNTA (0.42) | FNTAFNTBNPSR1TDP1TSHR | |
| SCHEMBL6179814 | 0.78 | FNTA (0.46) | FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL6180669 | 0.75 | FNTA (0.46) | FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL6767304 | 0.70 | GAA (0.55) | FNTAFNTBNPSR1TSHRPOLB | |
| SCHEMBL7682332 | 0.69 | FNTA (0.47) | FNTAFNTBTDP1TSHRPOLB | |
| SCHEMBL7682279 | 0.68 | FNTA (0.49) | FNTAFNTBPOLBCNR1CNR2 | |
| SCHEMBL15226049 | 0.67 | KDM4E (0.48) | NPSR1TSHRPOLBALDH1A1HTT | |
| SCHEMBL15225779 | 0.65 | POLB (0.47) | NPSR1TSHRPOLBALDH1A1HTT | |
| SCHEMBL6923290 | 0.61 | ALDH1A1 (0.59) | TDP1ALDH1A1CYP3A4CYP2C19HPGD | |
| SCHEMBL6922657 | 0.61 | ALDH1A1 (0.59) | TDP1ALDH1A1CYP3A4CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140909-B1 | NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | SCHERING CORP (US) | 2005-07-06 | — | — | EP | disclosed |
| US-6432959-B1 | ANTITUMOR AGENTS | SCHERING CORPORATION | 2002-08-13 | — | — | US | disclosed |