SCHEMBL6180166

SCHEMBL6180166

CCOC(Cl)CC(Cl)(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7694221 0.78 THRB (0.32) THRBLMNA
SCHEMBL9494334 0.71
SCHEMBL11486807 0.71 THRB (0.44) THRBLMNA
SCHEMBL5075134 0.71
SCHEMBL31296259 0.71 THRB (0.44) THRBLMNA
SCHEMBL339818 0.69
SCHEMBL29732253 0.69
SCHEMBL1772944 0.67
SCHEMBL8109397 0.67
SCHEMBL11661782 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113896639-A 3-methoxy methyl acrylate preparation system 昂吉(上海)环保新材料科技有限公司 2022-01-07 CN disclosed
CN-113896634-A Preparation method of 3-methoxy methyl acrylate 昂吉(上海)环保新材料科技有限公司 2022-01-07 CN disclosed
CN-109746042-B Catalyst for synthesizing 3-methoxy methyl acrylate and solid-supported and using method 衢州学院 2021-08-27 CN disclosed
EP-1200414-B1 PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIMIDINES BASF AG (DE) 2005-04-20 EP disclosed
WO-2003076409-A1 DERIVATIVES OF 1-PHENYL-3-PHENYLPYRAZOLE AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2003-09-18 WO disclosed
US-6559307-B2 Cyclization of an amidine compound with a vinylcarbonyl compound BASF AKTIENGESELLSCHAFT (DE) 2003-05-06 US disclosed
US-20020004600-A1 Process for the preparation of substituted pyrimidines AMERICAN CYANAMID COMPANY 2002-01-10 US disclosed
US-6281358-B1 REACTING AN AMIDINE COMPOUND WITH A VINYLCARBONYL COMPOUNDIN INERT SOLVENT IN PRESENCE OF BASE AMERICAN CYANAMID COMPANY 2001-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004600-A1 Process for the preparation of substituted pyrimidines XRN2, HPRT1, POLR2H THRB 2561/4885LMNA 926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.