SCHEMBL7694221

SCHEMBL7694221

CCOC(Cl)CC(Cl)(Cl)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7691135 0.79 CES1 (0.31)
SCHEMBL6180166 0.78 THRB (0.36) THRBLMNA
SCHEMBL7696199 0.75 MEN1 (0.31)
SCHEMBL7693613 0.69
SCHEMBL9580367 0.69 ALDH1A1 (0.30)
SCHEMBL10904850 0.68 TDP1 (0.37) LMNA
SCHEMBL11269662 0.67
SCHEMBL31296259 0.66 THRB (0.44) THRBLMNA
SCHEMBL5075134 0.66
SCHEMBL11486807 0.66 THRB (0.44) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12077505-B2 Preparation of sulfonamide herbicide process intermediates CORTEVA AGRISCIENCE LLC (US) 2024-09-03 US disclosed
US-20220024873-A1 PREPARATION OF SULFONAMIDE HERBICIDE PROCESS INTERMEDIATES Geneva Agriscience LLC (US) 2022-01-27 US disclosed
US-20220024873-A1 PREPARATION OF SULFONAMIDE HERBICIDE PROCESS INTERMEDIATES Geneva Agriscience LLC (US) 2022-01-27 US disclosed
CN-113272277-A Sulfonamide herbicide process intermediates preparation 科迪华农业科技有限责任公司 2021-08-17 CN disclosed
WO-2020139734-A1 PREPARATION OF SULFONAMIDE HERBICIDE PROCESS INTERMEDIATES DOW AGROSCIENCES LLC (US) 2020-07-02 WO disclosed
WO-2002053518-A2 HALOGENATED-α,β-UNSATURATED-β-(SUBSTITUTED-AMINO) CARBOXYLATE ESTERS HONEYWELL INTERNATIONAL, INC. (US) 2002-07-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12077505-B2 Preparation of sulfonamide herbicide process intermediates ORMDL3, STS, CBR3 THRB 2463/4885LMNA 2201/4885
US-20220024873-A1 PREPARATION OF SULFONAMIDE HERBICIDE PROCESS INTERMEDIATES ORMDL3, STS, CBR3 THRB 2463/4885LMNA 2201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.