Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 7/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178779 | 0.90 | TACR1 (0.38) | TACR1ALDH1A1F2XIAPTAAR1 | |
| SCHEMBL6181640 | 0.85 | F2 (0.39) | SCN5ASCN3AF2 | |
| SCHEMBL6093180 | 0.85 | TAAR1 (0.41) | SCN5ASCN3ATACR1F2XIAP | |
| Hydrochloric Acid SCHEMBL6093286 | 0.85 | DPP4 (0.40) | SCN5ASCN3AF2 | |
| SCHEMBL6179624 | 0.81 | F2 (0.41) | SCN5ASCN3AF2SMN1; SMN2PRSS1 | |
| SCHEMBL6181452 | 0.80 | XIAP (0.40) | TACR1F2XIAPPRSS1 | |
| SCHEMBL6180898 | 0.76 | SCN4A (0.38) | TACR1XIAPTAAR1 | |
| SCHEMBL6179716 | 0.75 | DPP4 (0.41) | XIAP | |
| SCHEMBL6093203 | 0.75 | XIAP (0.43) | TACR1XIAPTAAR1 | |
| SCHEMBL6178208 | 0.75 | XIAP (0.43) | TACR1XIAPTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287018-B1 | THROMBIN INHIBITORS | LEK TOVARNA FARMACEVTSKIH (SI) | 2005-01-19 | — | — | EP | claimed |