Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 4/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 5/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178779 | 0.90 | TACR1 (0.38) | XIAPSCN4ATACR1F2 | |
| SCHEMBL6180622 | 0.85 | SCN4A (0.39) | XIAPSCN4AF2 | |
| SCHEMBL6178104 | 0.85 | SCN4A (0.39) | XIAPSCN4AF2 | |
| SCHEMBL6195489 | 0.85 | XIAP (0.42) | XIAPSCN4AACELTA4HF2 | |
| Hydrochloric Acid SCHEMBL6094489 | 0.84 | DPP4 (0.47) | ACEF2 | |
| SCHEMBL6094570 | 0.83 | XIAP (0.49) | XIAPACETACR1F2PRSS1 | |
| SCHEMBL6095928 | 0.80 | XIAP (0.46) | XIAPF2PRSS1 | |
| SCHEMBL6180217 | 0.80 | SCN5A (0.38) | XIAPTACR1F2PRSS1 | |
| SCHEMBL6178057 | 0.78 | KDM4E (0.41) | XIAPSCN4AF2 | |
| SCHEMBL6181742 | 0.78 | KDM4E (0.41) | XIAPSCN4AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287018-B1 | THROMBIN INHIBITORS | LEK TOVARNA FARMACEVTSKIH (SI) | 2005-01-19 | — | — | EP | claimed |