Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181452 | 0.90 | XIAP (0.40) | TACR1SCN4AXIAPF2 | |
| SCHEMBL6180217 | 0.90 | SCN5A (0.38) | TACR1XIAPALDH1A1TAAR1F2 | |
| SCHEMBL6180898 | 0.86 | SCN4A (0.38) | TACR1SCN4AXIAPCASP1TAAR1 | |
| SCHEMBL6179716 | 0.85 | DPP4 (0.41) | SCN4AXIAPHTT | |
| SCHEMBL6093203 | 0.85 | XIAP (0.43) | TACR1XIAPTAAR1 | |
| SCHEMBL6178208 | 0.85 | XIAP (0.43) | TACR1XIAPTAAR1 | |
| Hydrochloric Acid SCHEMBL6196562 | 0.85 | DPP4 (0.42) | SCN4AXIAPHTT | |
| Hydrochloric Acid SCHEMBL6094296 | 0.85 | DPP4 (0.42) | SCN4AXIAPHTT | |
| SCHEMBL6178104 | 0.79 | SCN4A (0.39) | SCN4AXIAPCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6180622 | 0.79 | SCN4A (0.39) | SCN4AXIAPCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287018-B1 | THROMBIN INHIBITORS | LEK TOVARNA FARMACEVTSKIH (SI) | 2005-01-19 | — | — | EP | claimed |