Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | CSGALNACT1 | Q8TDX6 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673378 | 1.00 | MRGPRX4 (0.46) | MRGPRX4DGAT1CSGALNACT1MCL1SMN1; SMN2 | |
| SCHEMBL6174846 | 0.80 | SMN1; SMN2 (0.52) | MRGPRX4SMN1; SMN2MAPK1ALDH1A1KDM4E | |
| SCHEMBL31239091 | 0.80 | SMN1; SMN2 (0.52) | MRGPRX4SMN1; SMN2MAPK1ALDH1A1KDM4E | |
| SCHEMBL8673382 | 0.79 | P2RX7 (0.46) | SMN1; SMN2MAPK1ALDH1A1KDM4EKMT2A | |
| SCHEMBL6177347 | 0.78 | MAPK1 (0.52) | MRGPRX4SMN1; SMN2MAPK1ALDH1A1KDM4E | |
| SCHEMBL29712887 | 0.78 | MAPK1 (0.52) | MRGPRX4SMN1; SMN2MAPK1ALDH1A1KDM4E | |
| SCHEMBL6176107 | 0.78 | ALDH1A1 (0.47) | SMN1; SMN2MAPK1ALDH1A1KDM4EKMT2A | |
| SCHEMBL6177094 | 0.78 | ALDH1A1 (0.52) | SMN1; SMN2MAPK1ALDH1A1KDM4EKMT2A | |
| SCHEMBL8673381 | 0.77 | MAPK1 (0.43) | SMN1; SMN2MAPK1ALDH1A1KDM4EKMT2A | |
| SCHEMBL6177600 | 0.77 | L3MBTL1 (0.47) | SMN1; SMN2MAPK1ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708756-B1 | SUBSTITUTED 2-PHENYLPYRIDINES WITH HERBICIDAL ACTION | BASF AG (DE) | 2005-06-01 | — | — | EP | disclosed |
| CN-1127504-A | Substituted 2-phenylpyridines with herbicidal action | BASF AG (DE) | 1996-07-24 | — | — | CN | disclosed |
| EP-0708756-A1 | SUBSTITUTED 2-PHENYLPYRIDINES WITH HERBICIDAL ACTION | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002580-A2 | SUBSTITUTED 2-PHENYLPYRIDINES WITH HERBICIDAL ACTION | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-26 | — | — | WO | disclosed |