SCHEMBL618128

SCHEMBL618128

CC(=O)CNC(=O)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.63
LMNA P02545 1/20 0.56
POLB P06746 1/20 0.56
GPR139 Q6DWJ6 1/20 0.56
HPGD P15428 2/20 0.53
ALDH1A1 P00352 1/20 0.53
NAAA Q02083 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
NPC1 O15118 4/20 0.52
RAB9A P51151 4/20 0.52
PRSS1 P07477 2/20 0.50
CTSG P08311 2/20 0.50
CTRB1 P17538 2/20 0.50
CMA1 P23946 2/20 0.50
HDAC1 Q13547 2/20 0.50
HDAC6 Q9UBN7 2/20 0.50
EPHX2 P34913 1/20 0.50
HDAC3 O15379 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13203130 0.89 KDM4E (0.53) GAALMNAPOLBALDH1A1SMN1; SMN2
SCHEMBL28968620 0.89 RAB9A (0.59) LMNAPOLBHPGDSMN1; SMN2NPC1
SCHEMBL17299366 0.86 KDM4E (0.67) LMNAPOLBHPGDCA1CA9
SCHEMBL19149894 0.84 MMP1 (0.70) LMNAPOLBHPGDALDH1A1SMN1; SMN2
SCHEMBL24991661 0.84 GAA (0.59) GAALMNAPOLBGPR139HPGD
SCHEMBL10670423 0.83 GAA (0.53) GAALMNAPOLBGPR139HPGD
SCHEMBL13202996 0.83 RAB9A (0.49) POLBALDH1A1SMN1; SMN2NPC1RAB9A
Acetic Acid SCHEMBL7505127 0.83 GAA (0.63) GAALMNAPOLBGPR139HPGD
SCHEMBL22030672 0.83 GAA (0.68) GAALMNAPOLBGPR139SMN1; SMN2
Hippuric Acid SCHEMBL428479 0.83 GAA (0.68) GAALMNAPOLBGPR139SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 333 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020048797-A1 Production of optically active 2-substituted tetrahydropyran-4-ones ZENECA LIMITED 2002-04-25 US claimed
US-20020042437-A1 Fungicidal mixtures SCHELBERGER KLAUS (DE) 2002-04-11 US claimed
EP-0984687-B1 FUNGICIDAL MIXTURES BASF AG (DE) 2001-11-14 EP claimed
EP-1039805-A2 FUNGICIDE MIXTURES BASED ON AMIDE COMPOUNDS AND PYRIDINE DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2000-10-04 EP claimed
EP-0815727-B1 Use of N-acetonylbenzamides for controlling resistant fungi ROHM & HAAS (US) 2000-08-16 EP claimed
EP-0984687-A1 FUNGICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2000-03-15 EP claimed
WO-1999031951-A2 FUNGICIDE MIXTURES BASED ON PYRIDINE CARBOXAMIDES BASF AKTIENGESELLSCHAFT (DE) 1999-07-01 WO claimed
US-5891918-A Method for controlling resistant fungi ROHM AND HAAS COMPANY (US) 1999-04-06 US claimed
WO-1998053684-A1 FUNGICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 1998-12-03 WO claimed
EP-0815727-A1 Method for controlling resistant fungi ROHM AND HAAS COMPANY (US) 1998-01-07 EP claimed
JP-10095757-A None JP disclosed
JP-9124413-A None JP disclosed
JP-6211765-A None JP disclosed
JP-11269011-A None JP disclosed
JP-11310505-A None JP disclosed
EP-0173453-B1 SUBSTITUTED N-ACETONYLBENZAMIDES AND THEIR USE AS FUNGICIDES ROHM AND HAAS COMPANY (US) 1988-07-13 EP disclosed
EP-0173453-B1 SUBSTITUTED N-ACETONYLBENZAMIDES AND THEIR USE AS FUNGICIDES ROHM AND HAAS COMPANY (US) 1988-07-13 EP disclosed
EP-0173453-A1 Substituted N-acetonylbenzamides and their use as fungicides ROHM AND HAAS COMPANY (US) 1986-03-05 EP disclosed
EP-0173453-A1 Substituted N-acetonylbenzamides and their use as fungicides ROHM AND HAAS COMPANY (US) 1986-03-05 EP disclosed
EP-0173453-A1 Substituted N-acetonylbenzamides and their use as fungicides ROHM AND HAAS COMPANY (US) 1986-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020042437-A1 Fungicidal mixtures CBR1, CBR3, CYP1B1 GAA 2424/4885LMNA 1580/4885POLB 2147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.