Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13467941 | 0.85 | CCNE1 (0.56) | ALDH1A1SMN1; SMN2KDM4EHPGDNPC1 | |
| SCHEMBL13467940 | 0.83 | NPC1 (0.46) | ALDH1A1SMN1; SMN2KDM4EHPGDNPC1 | |
| SCHEMBL15100311 | 0.82 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KDM4EHPGDNPC1 | |
| SCHEMBL5025993 | 0.75 | SCD (0.45) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL19458500 | 0.75 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2KDM4EHPGDNPC1 | |
| SCHEMBL27518079 | 0.73 | VNN1 (0.40) | ALDH1A1SMN1; SMN2KDM4EHPGDNPC1 | |
| SCHEMBL5025395 | 0.73 | CDK2 (0.48) | ALDH1A1SMN1; SMN2KDM4EHPGDNPC1 | |
| SCHEMBL27518243 | 0.73 | KCNN4 (0.35) | ALDH1A1SMN1; SMN2KDM4EHPGDNPC1 | |
| SCHEMBL5521898 | 0.72 | LCK (0.72) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL1686728 | 0.71 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298057-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N- SULFATED BETA LACTAMS | ARIXA PHARMACEUTICALS, INC. | 2017-10-19 | — | — | US | disclosed |
| WO-2017180794-A1 | DEUTERATED O-SULFATED BETA-LACTAM HYDROXAMIC ACIDS AND DEUTERATED N-SULFATED BETA-LACTAMS | SKYLINE ANTIINFECTIVES, INC. (US) | 2017-10-19 | — | — | WO | disclosed |
| US-9630977-B2 | Cephalosporin derivatives and pharmaceutical compositions thereof | LEGOCHEM BIOSCIENCES, INC. (KR) | 2017-04-25 | — | — | US | disclosed |
| US-20130178455-A1 | NOVEL CEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LEGOCHEM BIOSCIENCES, INC (US) | 2013-07-11 | — | — | US | disclosed |
| US-6916803-B2 | 3-(Heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents | PANTHERIX, LTD. (GB) | 2005-07-12 | — | — | US | disclosed |
| EP-1322648-B1 | 3-(HETEROARYL ACETAMIDO)-2-OXO-AZETIDINE-1-SULFONIC ACIDS DERIVATIVES AS ANTIBACTERIAL AGENTS | PANTHERIX LTD (GB) | 2005-06-29 | — | — | EP | disclosed |
| US-20040019203-A1 | 3-(Heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents | REMPEX PHARMACEUTICALS, INC. | 2004-01-29 | — | — | US | disclosed |
| EP-1322648-A1 | 3-(HETEROARYL ACETAMIDO)-2-OXO-AZETIDINE-1-SULFONIC ACIDS DERIVATIVES AS ANTIBACTERIAL AGENTS | Pantherix Limited (GB) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002022613-A1 | 3-(HETEROARYL ACETAMIDO)-2-OXO-AZETIDINE-1-SULFONIC ACIDS DERIVATIVES AS ANTIBACTERIAL AGENTS | PANTHERIX LIMITED (GB) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298057-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N- SULFATED BETA LACTAMS | DDOST, LBR, STS | ALDH1A1 3218/4885SMN1; SMN2 2168/4885KDM4E 4367/4885 |
| US-20040019203-A1 | 3-(Heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents | Q6ZSR9, SOS1, SOS2 | ALDH1A1 988/4885SMN1; SMN2 815/4885KDM4E 4822/4885 |
| US-20130178455-A1 | NOVEL CEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | CSDE1, CELA1, ABCC1 | ALDH1A1 1077/4885SMN1; SMN2 4372/4885KDM4E 2252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.