Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15100311 | 0.88 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2HPGDTSHRKDM4E | |
| SCHEMBL13467941 | 0.78 | CCNE1 (0.56) | ALDH1A1SMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL17595785 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EMAPTGABRA5 | |
| SCHEMBL6181698 | 0.75 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL13467940 | 0.73 | NPC1 (0.46) | ALDH1A1SMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL27543447 | 0.70 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2TSHRKDM4ENPC1 | |
| SCHEMBL8628745 | 0.70 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL27518079 | 0.69 | VNN1 (0.40) | ALDH1A1SMN1; SMN2HPGDTSHRKDM4E | |
| SCHEMBL3983323 | 0.69 | RAB9A (0.67) | ALDH1A1SMN1; SMN2HPGDTSHRKDM4E | |
| SCHEMBL7763018 | 0.69 | MEN1 (0.47) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10093666-B2 | Deuterated O-sulfated beta lactam hydroxamic acids and deuterated N-sulfated beta lactams | ARIXA PHARMACEUTICALS, INC. (US) | 2018-10-09 | — | — | US | disclosed |
| US-20180148439-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N-SULFATED BETA LACTAMS | ARIXA PHARMACEUTICALS, INC. | 2018-05-31 | — | — | US | disclosed |
| US-20170298057-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N- SULFATED BETA LACTAMS | ARIXA PHARMACEUTICALS, INC. | 2017-10-19 | — | — | US | disclosed |
| WO-2017180794-A1 | DEUTERATED O-SULFATED BETA-LACTAM HYDROXAMIC ACIDS AND DEUTERATED N-SULFATED BETA-LACTAMS | SKYLINE ANTIINFECTIVES, INC. (US) | 2017-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298057-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N- SULFATED BETA LACTAMS | DDOST, LBR, STS | ALDH1A1 3218/4885SMN1; SMN2 2168/4885HPGD 122/4885 |
| US-20180148439-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N-SULFATED BETA LACTAMS | DDOST, LBR, STS | ALDH1A1 3218/4885SMN1; SMN2 2168/4885HPGD 122/4885 |
| US-10093666-B2 | Deuterated O-sulfated beta lactam hydroxamic acids and deuterated N-sulfated beta lactams | DDOST, LBR, STS | ALDH1A1 3218/4885SMN1; SMN2 2168/4885HPGD 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.