Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399530 | 0.79 | CYP1A2 (0.44) | CYP3A4CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL9766041 | 0.77 | CA1 (0.36) | CYP3A4CYP1A2CYP2C19MAPK1MEN1 | |
| SCHEMBL2687218 | 0.76 | PKM (0.41) | CYP3A4CYP1A2CYP2C19MAPTALDH1A1 | |
| SCHEMBL923487 | 0.74 | MAPT (0.40) | MAPK1MAPTALDH1A1CES2CES1 | |
| SCHEMBL16253909 | 0.73 | KMT2A (0.48) | CYP3A4GAAMEN1KMT2AVCAM1 | |
| SCHEMBL25992427 | 0.72 | CYP1A2 (0.44) | CYP3A4CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL14208999 | 0.72 | CYP1A2 (0.39) | CYP3A4CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL1994831 | 0.71 | TDP1 (0.41) | CYP3A4VCAM1ALDH1A1TSHRHIF1A | |
| SCHEMBL29162746 | 0.69 | CES2 (0.56) | CYP3A4CYP1A2CYP2C19GAAMEN1 | |
| SCHEMBL25992038 | 0.69 | CA1 (0.47) | CYP3A4CYP1A2CYP2C19GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129071-B1 | PHENYL-SUBSTITUTED CYCLIC ENAMINONES | BAYER CROPSCIENCE AG (DE) | 2005-10-26 | — | — | EP | disclosed |
| US-20030130125-A1 | Phenyl-substituted cyclic enaminones | FISCHER REINER (DE) | 2003-07-10 | — | — | US | disclosed |
| US-6455472-B1 | HERBICIDES, ACARICIDES, NEMATICIDES AND INSECTICIDES FOR CROPS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-24 | — | — | US | disclosed |
| EP-1129071-A1 | PHENYL-SUBSTITUTED CYCLIC ENAMINONES | Bayer Aktiengesellschaft (DE) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027812-A1 | PHENYL-SUBSTITUTED CYCLIC ENAMINONES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130125-A1 | Phenyl-substituted cyclic enaminones | DDT, CYP19A1, KCNA1 | CYP3A4 295/4885CYP1A2 24/4885CYP2C19 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.