Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | CCR4 | P51679 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184367 | 0.86 | KDM4E (0.55) | KDM4ECCR4GAATSHRNFKBIA | |
| SCHEMBL5111149 | 0.86 | CCR4 (0.48) | KDM4ECCR4GAANFKBIARELA | |
| SCHEMBL6197275 | 0.82 | CCR4 (0.44) | KDM4ECCR4GAATSHRALDH1A1 | |
| SCHEMBL6181633 | 0.81 | KDM4E (0.53) | KDM4ECCR4GAATSHRALDH1A1 | |
| SCHEMBL6183896 | 0.80 | CCR4 (0.64) | KDM4ECCR4ALDH1A1CCR2SMN1; SMN2 | |
| SCHEMBL1731933 | 0.80 | CCR4 (0.67) | CCR4 | |
| SCHEMBL5106613 | 0.75 | CCR4 (0.47) | KDM4ECCR4GAATSHRNFKBIA | |
| SCHEMBL6185129 | 0.75 | CCR4 (0.37) | CCR4GAAALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL6182958 | 0.74 | CCR4 (0.74) | KDM4ECCR4SMN1; SMN2MEN1MAPT | |
| SCHEMBL1733169 | 0.71 | CCR4 (0.71) | CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458715-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2005-12-07 | — | — | EP | disclosed |