Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | HTR7 | P34969 | 5/20 | 0.40 |
| ▸ | HTR6 | P50406 | 5/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6182962 | 0.88 | HTR2A (0.55) | DRD2HTR7HTR6HTR2A | |
| SCHEMBL6187862 | 0.85 | HTR1D (0.46) | HTR7HTR2A | |
| SCHEMBL6184588 | 0.85 | HTR2A (0.58) | DRD2HTR7HTR6HTR2A | |
| SCHEMBL6182991 | 0.82 | HTR2A (0.53) | TBXA2RDRD2HTR7HTR6HTR2A | |
| SCHEMBL6186397 | 0.82 | HTR1D (0.42) | HTR7 | |
| SCHEMBL6183970 | 0.82 | TBXA2R (0.56) | TBXA2RTBXAS1 | |
| Hydrochloric Acid SCHEMBL7225841 | 0.82 | HTR2A (0.52) | DRD2HTR7HTR6HTR2AHTR1A | |
| SCHEMBL6182420 | 0.81 | ABCB1 (0.50) | TBXA2RTBXAS1HTR7 | |
| SCHEMBL6183084 | 0.80 | TBXA2R (0.54) | TBXA2RTBXAS1 | |
| SCHEMBL7225705 | 0.79 | HTR2A (0.56) | DRD2HTR7HTR6HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541471-B1 | Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist | LES LABORATOIRES SERVIER (FR) | 2003-04-01 | — | — | US | disclosed |