SCHEMBL6183039

SCHEMBL6183039

CC(C)c1cccc(C(C)C)c1NC(=O)N(Cc1cccc(C(N)=O)c1)C(c1ccccn1)C1CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
UBE2M P61081 1/20 0.37
DCUN1D1 Q96GG9 1/20 0.37
NMBR P28336 2/20 0.35
GRPR P30550 1/20 0.35
KMT2A Q03164 2/20 0.34
LMNA P02545 1/20 0.34
F2RL1 P55085 1/20 0.34
EPHX1 P07099 1/20 0.34
PARP14 Q460N5 1/20 0.34
MEP1B Q16820 1/20 0.33
MEN1 O00255 1/20 0.33
PTGES O14684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6805345 0.87 UBE2M (0.43) UBE2MDCUN1D1NMBRGRPRKMT2A
SCHEMBL6803558 0.87 UBE2M (0.39) UBE2MDCUN1D1NMBRGRPR
SCHEMBL6186318 0.86 SOAT1 (0.40) UBE2MDCUN1D1NMBRGRPR
SCHEMBL6185668 0.85 MEN1 (0.37) UBE2MDCUN1D1NMBRGRPRKMT2A
SCHEMBL6801844 0.84 UBE2M (0.41) UBE2MDCUN1D1NMBRGRPRKMT2A
SCHEMBL6808030 0.82 UBE2M (0.39) UBE2MDCUN1D1NMBRGRPRKMT2A
SCHEMBL6183997 0.82 NMBR (0.41) UBE2MDCUN1D1NMBRGRPRKMT2A
SCHEMBL6183517 0.81 NMBR (0.37) UBE2MDCUN1D1NMBRGRPR
SCHEMBL6803628 0.81 UBE2M (0.47) UBE2MDCUN1D1NMBRGRPRKMT2A
SCHEMBL6185224 0.80 NSD2 (0.39) NMBRGRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1501800-A1 BOMBESIN ANTAGONISTS Warner-Lambert Company LLC (US) 2005-02-02 EP disclosed
US-20040063643-A1 Bombesin antagonists PFIZER INC. 2004-04-01 US disclosed
WO-2003092670-A1 BOMBESIN ANTAGONISTS WARNER-LAMBERT COMPANY LLC (US) 2003-11-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063643-A1 Bombesin antagonists BRS3, NPSR1, GNRHR UBE2M 3897/4885DCUN1D1 2124/4885NMBR 211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.