SCHEMBL6805345

SCHEMBL6805345

CC(C)c1cccc(C(C)O)c1NC(=O)N(Cc1ccccc1)C(c1ccccn1)C1CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
UBE2M P61081 2/20 0.43
DCUN1D1 Q96GG9 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 1/20 0.37
NMBR P28336 1/20 0.37
GRPR P30550 1/20 0.37
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SOAT2 O75908 1/20 0.36
SOAT1 P35610 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6801844 0.91 UBE2M (0.41) UBE2MDCUN1D1SMN1; SMN2LMNANMBR
SCHEMBL6186318 0.90 SOAT1 (0.40) UBE2MDCUN1D1NMBRGRPRKDM4E
SCHEMBL6803558 0.90 UBE2M (0.39) UBE2MDCUN1D1NMBRGRPRKDM4E
SCHEMBL6808030 0.88 UBE2M (0.39) UBE2MDCUN1D1SMN1; SMN2LMNANMBR
SCHEMBL6803628 0.87 UBE2M (0.47) UBE2MDCUN1D1SMN1; SMN2LMNANMBR
SCHEMBL6183039 0.87 UBE2M (0.37) UBE2MDCUN1D1LMNANMBRGRPR
SCHEMBL6183997 0.85 NMBR (0.41) UBE2MDCUN1D1SMN1; SMN2LMNANMBR
SCHEMBL6185668 0.85 MEN1 (0.37) UBE2MDCUN1D1SMN1; SMN2NMBRGRPR
SCHEMBL6808987 0.84 NMBR (0.38) UBE2MDCUN1D1SMN1; SMN2NMBRGRPR
SCHEMBL6183517 0.81 NMBR (0.37) UBE2MDCUN1D1NMBRGRPRSOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040063643-A1 Bombesin antagonists PFIZER INC. 2004-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063643-A1 Bombesin antagonists BRS3, NPSR1, GNRHR UBE2M 3897/4885DCUN1D1 2124/4885SMN1; SMN2 1091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.